Playback is currently unavailable for S1 E1 · Pilot. Episode details remain available below.
Common Side Effects
Former high school lab partners Marshall and Frances begin to unravel a conspiracy involving big pharma and the federal government to suppress knowledge of a rare mushroom that may hold the key to curing all the world’s diseases.
- Created by:
- Joseph Bennett, Steve Hely
- Cast:
- Dave King, Emily Pendergast, Mike Judge, Martha Kelly
- Language:
- English
- Country:
- United States of America
- Network:
- Adult Swim
Episode guide
Seasons
Season 1
Episodes
E01
Episode 1
★ 7.9Pilot
2025-02-02 · 22mMarshall meets his old high school classmate Frances and lets her in on a world-changing secret.
Current episode
E02
Episode 2
★ 7.6Lakeshore Limited
2025-02-02 · 23mMarshall's forced on the run as the DEA pursues him.
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E03
Episode 3
★ 7.9Hildy
2025-02-09 · 23mMarshall visits an old mentor as new pressures mount.
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E04
Episode 4
★ 7.6Dumpsite
2025-02-16 · 23mFrances tracks down Marshall in an unlikely location.
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E05
Episode 5
★ 7.1Star-Tel-Lite
2025-02-23 · 22mMarshall, Frances, and their crazy neighbors deal with the aftermath of a dangerous incident.
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E06
Episode 6
★ 7.5In the System
2025-03-02 · 23mStuck in jail, Marshall faces new threats.
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E07
Episode 7
★ 7.4Blowfish
2025-03-09 · 23mA chance encounter offers a risky opportunity for escape.
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E08
Episode 8
★ 7.2Amelia & Wyatt
2025-03-16 · 22mMarshall and his new ally make a bold move.
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E09
Episode 9
★ 7.6Cliff's Edge
2025-03-23 · 23mMarshall's mushroom project grows out of hand.
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E10
Episode 10
★ 7.9Raid
2025-03-30 · 23mDangerous forces converge on Marshall's camp.
Watch progress · Not trackedCast
Dave King
Marshall Cuso (voice)
Emily Pendergast
Frances Applewhite (voice)
Mike Judge
Rick Kruger (voice)
Martha Kelly
Agent Harrington (voice)
Joseph Lee Anderson
Agent Copano (voice)